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Nature Medicine asks leading researchers to name their top clinical trial for 2025, from genetherapies for prion disease and sickle-cell disease to digital tools for cancer and mental health

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A unified Linear Viscoelastic Model of the cell nucleus defines the mechanical contributions of Lamins and Chromatin

Best practices include: Using clean work surfaces Using sterile tools when required by the model Labeling all prepared materials clearly Avoiding unnecessary container transfers Separating materials between experiments Cleaning equipment before and after use Avoiding cross-contact between samples Discarding compromised materials according to laboratory policy Contamination control improves both safety and reproducibility