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But the studies measured the levels of a single chemical at one point in time, says McAlonan

BPC-157 is also not an FDA-approved treatment, and they've noted safety concerns surrounding this peptide, citing that it may contain impurities and may trigger an unwanted immune system response that could be dangerous

A 2020 review on the safety of BPC-157 in preclinical (animal) studies states that the peptide did not show any test-related effects in the single-dose toxicity study and that it was well tolerated in repeat-dose evaluations.16 Other animal studies and reviews mention that BPC-157 has no reported toxicity or that it was without a lethal dose in toxicology studies.14 17 Even the authors of a small human study on BPC-157 for interstitial cystitis note that no one dropped out of the study, and no adverse events were reported.18 We want to highlight that most of the relevant studies have been conducted on animals, and more human research is needed

A few key takeaways Some important things to consider in light of this letter that has import into compounding and drug production in general: This letter documents systemic failure, not isolated incidents