inhaled glutathione asthma bronchospasm sulfite The Treatment of Pulmonary Diseases and Respiratory-Related Conditions with (Nebulized or Aerosolized) Oxidative Stress and Risk Factors

[Abstract]2025 Dec;333(Pt 1):148831

H 2 S donor GYY4137 has been confirmed to in vivo protect against ischemia-reperfusion injury and attenuate histopathological changes after testicular torsion/detorsion, as well as mediate an increase in antioxidant capacity (89, 92), reduce apoptosis of spermatogenic cells, and increase the expression level of heat shock protein 70 (89), which helps prevent cell apoptosis during heat stress in testicular cells (98), preserve sperm motility in cryopreserved bull sperm (99), and protect proteins and DNA under stress conditions (100)

Since the latter study had a placebo group which had redox and methylation biomarkers measured at the beginning and end of the intervention, we use this placebo group as a control group for all three studies in order to determine if the changes in redox and methylation metabolism were significant as a result of the three interventions

Jena KK, Kolapalli SP, Mehto S, Nath P, Das B, Sahoo PK, et al