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Oxidative stress and mitochondrial dysfunction Mitochondria are not only the primary site of ROS production but also major targets of oxidative stress

Consistent with our observations, fluorine has been reported to increase the binding affinity of small molecules to their biological targets 41 and ENDO12, with its fluorine group, may also have better permeability than ENDO3 (refs

Wu Y, Yang Z, How J, Xu H, Chen L, Li K.Overexpression of a peroxidase gene (AtPrx64) of Arabidopsis thaliana in tobacco improves plants tolerance to aluminum stress