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Two inhibitors of cysteine proteases (cystatins 39,40 ) and two -2-macroglobulin homologues (I39) were also identified, as were three inhibitor of apoptosis proteins (I32), one of which is highly expressed in adults, where it may function to regulate one or more of the four schistosome caspases

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(PubMed) Iyer R, Gupta A, Khan A, Hiremath S, Lokhandwala Y

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In conclusion, GLN is essential for the treatment of leukemia and is an effective therapeutic strategy

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Among 17 members in humans and 16 members in mice, PARP1 alone is responsible for about 90% of all NAD + used by the PARP protein family [49]

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