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Unlike direct testosterone use, which may suppress natural production, HCG supports the bodys ability to produce testosterone endogenously

Preclinical and clinical programs must therefore not only demonstrate that hydrogels act as spacers and local delivery vehicles, but also define how tumor intrinsic factorsnotably histologic subtype (squamous cell carcinoma (SCC) versus adenocarcinoma (AC)) and HPV statusmodify radiosensitivity and the therapeutic benefit gained from hydrogel-mediated radiosensitization (see Table 3)

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