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One study reported that women who experienced at least five episodes of severe sunburns between the ages of 15 and 20 years were 80 percent more likely to develop melanoma later in life, compared to those who did not experience sunburns (267)

The connection between glutamate- and cysteine-induced cytotoxicity and cancer cell death may have initially inspired the concept of ferroptosis [20, 21], and research on oxidative stress-induced non-apoptotic cell death in neurons was reported in 2001 [22]

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