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CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis

This process facilitates the conversion of fibroblasts into myofibroblasts, suggesting that ferroptosis is involved in the pathological activation of fibroblasts in IPF

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Furthermore, another study indicated that the nephroprotective effect mediated through TLR-2 is in part attributed to activation of autophagy and knockout of TLR2 reduced expression of autophagy proteins and exacerbated renal dysfunction in the CP-induced AKI model (Liang et al., 2017)