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Description

Campbell DB, Sutcliffe JS, Ebert PJ, Militerni R, Bravaccio C, Trillo S, Elia M, Schneider C, Melmed R, Sacco R, Persico AM, Levitt P (2006)

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No consistent pattern was seen with the median t max across the groups (72, 48, 48 and 60 h for normal renal function and mild, moderate and severe renal impairment, respectively)

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Fatigue or drowsiness Due to its role in regulating melatonin and circadian rhythms, some may feel more tired initially

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