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10.1007/978-3-319-66682-2_15 62 HabigW

At end of treatment, hepatic hydroxyproline content was measured and the liver tissues were subjected to H&E and Sirius red staining followed by histological grading

FIGURE 4 APC (adenomatous polyposis coli) encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway

Furthermore, actively cycling CAR T cells isolated from a patient with a decade-long leukemia remission showed upregulation in LDHA and OXPHOS pathways, suggesting that both aerobic glycolysis and mitochondrial respiration are increased in CAR T cells that persist long-term 25