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An early treatment with 17--estradiol is neuroprotective against the long-term effects of neonatal ionizing radiation exposure

Existing studies are largely confined to small IVF cohorts or mixed POI/PCOS populations, often characterized by inconsistent dosing regimens, variable bioavailability, short follow-up periods, and the use of surrogate endpoints (e.g., AMH levels) rather than clinically meaningful outcomes such as live birth rates

Rg GUS and Bo GUS displayed complex substrate inhibition kinetics, and we were not able to fit these to established substrate inhibition models, including the uncompetitive substrate inhibition model, as determined in Equation 1, nor by the substrate inhibition models outlined in Lin et al