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Studies have also confirmed that the ERK/E2F1 pathway can cause gemcitabine resistance [277]

A single treatment of mice 42 days post infection (d.p.i.) with 1 (100 mg/kg i.p.) resulted in a 44% decrease in worm and a 40% reduction in egg burdens, respectively

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The conventional farmers practice (FP) and chemical-based practice (EP) showed moderate disease suppression and yield gains, while the untreated control consistently exhibited the highest disease incidence and lowest productivity across both seasons