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Activated calpains can aberrantly cleave several proteins that are critical for the integrity of neurons, such as spectrin, tubulin, tau, microtubule-associated protein, and neurofilaments (Wang and Po-Wai, 1994)

It might seem fragile or nerve-wracking with its Emergency Exit ability, which causes it to retreat when it loses half health, but this more often just means you can get a single attack in before it faints and have another shot at a priority move later in the battle