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Shared mechanisms between aging and cancer include oxidative stress-induced DNA damage and chronic inflammation

Oral glutathione is generally well-tolerated, with mild gastrointestinal side effects including flatulence and loose stools reported in some cases, which typically resolve spontaneously, and is considered possibly safe when used in doses up to 500 mg daily for up to 2 months

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[ref] In animal models of insomnia, Lactobacillus reuteri improved sleep by upregulating GABA and other inhibitory neurotransmitters