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It can be activated by death receptors, but signalling is transduced via caspase-independent pathways converging on RIPK3 and MLKL

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7:e2448

Often linked to low-fibre diets and ageing, it affects millions, especially those over 50

Studies are focusing on how these exposures interact with genetic factors to affect cancer development, such as multiple metabolic reprogramming and increased susceptibility to breast cancer