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How Scientists Studied Metformins Effect: In one study, over 3,000 adults at high risk for type 2 diabetes were enrolled in the Diabetes Prevention Program ( Journal of Clinical Endocrinology and Metabolism , April 2016)

It was the first peptide-based obesity drug to produce sustained double-digit weight loss in large randomized trials and served as the benchmark against which all newer incretin molecules are measured

Unlike some countries where patients might self-administer injections at home, the Japanese healthcare protocol typically requires a physician to oversee the process

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