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For example, in AD research, an FRG signature composed of genes such as DNA damage inducible transcript 4, mucin 1 and CD44 was found to not only distinguish patients with AD from healthy controls but also to predict disease severity and immune cell infiltration in the brain (43)

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J Immunol 173 : 42734276 Boulet S et al

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Clin Chem 45:459464 Wang XL, Yin F, Zhang GY (2017) DMGDH gene-related dimethylglycine dehydrogenase deficiency in a case

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