mechanisms for regenerating glutathione Frontiers Glutathione reductase - Wikipedia

Generally, glutamine can be converted in the mitochondria to supplement the tricarboxylic acid (TCA) cycle, or it can be completely oxidized to produce ATP

ACS Applied Materials & Interfaces, 2016, 8(9): 58875897 Wang S, Wang Z, Yu G, Zhou Z, Jacobson O, Liu Y, Ma Y, Zhang F, Chen Z Y, Chen X

the accumulation of sugar molecules in specific physiological milieus such as the serum, observed in case of diabetic and prediabetic individuals leads to the formation of non-native protein-sugar adducts more popularly known as Advanced Glycated End Products (Rungratanawanich et al., 2021)

Although prolonged GSH depletion induced triglyceride depletion and reduced epididymal adipose tissue in mice, it induced a sex-dependent requirement of NRF2 expression in the liver