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MTHFR C677C = normal MTHFR gene MTHFR C677T = heterozygous mutation (one mutation) MTHFR T677T = homozygous mutation (two mutations) MTHFR A1298A = normal MTHFR gene MTHFR A1298C = heterozygous mutation (one mutation) MTHFR C1298C = homozygous mutation (two mutations) MTHFR C677T + MTHFR A1298C = a compound heterozygous mutation in some combination of C 677T + A 1298C, C 677T + A1298 C, C677 T + A 1298C, or C677 T + A1298 C

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