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1a, left panel) or mRNA expression (Fig

Clinical studies provide indirect evidence of this process through fluid biomarkers: elevated serum and CSF levels of S100, an astrocytic protein that can leak into the bloodstream following BBB disruption and CSF during disease, have been reported in PD cohorts and correlate with disease severity, suggesting both astrocytic reactivity and vascular compromise (Sathe et al., 2012)

Gram flour has been a staple in Indian skincare routines for generations

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