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Mediated by the TOM complex, PINK1 undergoes trans-autophosphorylation and subsequent conformational rearrangement, thereby activating the E3 ubiquitin ligase activity of Parkin through its transition from an autoinhibited state to an active conformation (Riley et al., 2013)

For GI-specific research, oral bioavailability studies, or protocols that model oral administration routes, the capsule formulation is more appropriate

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You take antacids or other acid reflux medications frequently