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Because CGRP is essential for bone healing, the potential negative impact of these medications on bone regeneration warrants clinical investigation

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Statements Author contributions CH: Conceptualization, Formal Analysis, Writing original draft, Writing review and editing

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Participants received weekly subcutaneous injections of survodutide at 2.4 mg, 4.8 mg, or 6.0 mg, or placebo

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TIF images were standardized for intensity and analyzed using ImageJ software [National Institutes of Health (NIH), USA]

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