Nascimento et al., 2024) mainly by affecting skeletal muscle development ( The RPM supplementation during the last 28 days of gestation promoted an up-regulation in amino acid and glucose transporters in the placentome of cows, mediated by changes in gene transcription and mTOR signaling ( Efforts have been made to evaluate the effect of RPM supplementation during late pregnancy and its long-term effects on offspring performance
Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease
Itaconic acid exerts anti-inflammatory and antibacterial effects via promoting pentose phosphate pathway to produce ROS
2079-A NASH CIRRHOSIS: DISTINCT PHENOTYPICAL DIFFERENCES, MORE SYSTEMIC INFLAMMATION, AND MORE FRAIL THAN VIRAL-RELATED CIRRHOSIS Yu JUN Wong 1,2 , Heng Yi Tan 3 , Siew Yoon Yap 4 , Geraldine Lim 4 , Seok Hwee Khoo 4 , Jessica Tan 1 , Rahul Kumar 1,2 , Joan Khoo 5 , Rosario Helen Barbara 6 and Paul Edward Hutchinson 3 , (1)Department of Gastroenterology & Hepatology, Changi General Hospital, (2)Duke-Nus Medical School, Singhealth, (3)Flow Cytometry Laboratory, Life Sciences Institute, National University of Singapore, (4)Clinical Trial Research Unit, Changi General Hospital, (5)Department of Endocrinology, Changi General Hospital, (6)Department of Geriatric Medicine, Changi General Hospital Background: NASH is replacing viral hepatitis as the fastest-growing etiology of liver cirrhosis globally with limited therapeutic options
