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This situation was first reported in a boy with a deletion of exon 4 of the IGF-I gene (90) resulting in severe fetal and post-natal growth arrest, poor brain development and extreme insulin resistance with compensatory hyperinsulinemia and acanthosis nigricans

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Within-series precision and between-day precision for the gas chromatographic determination of cyanide in blood using a capillary column (from Eben & Lewalter, 1988) Precision n Cyanide in blood s (mg/l) % Within-series 17 0.19 5.4 17 0.39 0.9 17 2.11 0.7 Between-day 17 0.19 14.5 17 0.39 5.5 17 2.11 6.7 n = number of analyses performed s = relative standard deviation Recovery experiments were carried out using spiked blood samples

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