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CHOP-specific probes will permit the more careful dissection of the apoptotic UPR pathway in a fashion that will shed new insight into its potential as a therapeutic target

Next, 3 g of mouse anti-Strep II-Tag mAb or rabbit anti-DDDDK-tag (Flag) mAb, along with rabbit or mouse control IgG, was coupled to the protein A/G beads in 250 l of IP buffer at 40 C for 4 h on a rotating wheel

doi: 10.1016/j.jad.2024.11.069 69

48 Additionally, members of the six-transmembrane epithelial antigen of the prostate (STEAP) family (including STEAP2, STEAP3, and STEAP4) and duodenal cytochrome b (DCYTB) function as copper reductases, ensuring that copper (II) is maintained in its reduced state copper (I) to facilitating cellular uptake