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Description

(2014) S6:6574

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Cell Biol Toxicol 38 , 847864 (2022)

The thiol group of cysteine is subject to reversible and irreversible post-translational thiol-modifications that lead to inactivation or activation of the transcription factor