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Chronic inflammation, seen in conditions like rheumatoid arthritis and inflammatory bowel disease, is both a cause and consequence of sustained oxidative stress [13]

Trends Mol Med (2022) 28:25869

Benefits of repurposed monepantel for ALS sustained for up to 2 years

[7] A conserved ncRNA upstream of the icd gene which codes for NADP + -dependent isocitrate dehydrogenase (IDH) has been reported in bacterial genomes, due to its characteristics this ncRNA resembles previous regulatory motifs called riboswitches, icd-II ncRNA motif has been proposed as a strong candidate riboswitch