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Results: 366 patients were included who underwent liver transplant from 01/2018-12/2023

These effects were compared to those of untreated controls that were also maintained on a high-fat diet

Recently, a novel pathogenetic model has been proposed which postulated that changes in the local metabolic environment (pH, salt) may play a key role in the development of AS by induction of a Th17 pro-inflammatory phenotype through activation of glycosphingolipid sensors (encoded by the GPR genes in particularly GPR65 ) and serum and glucocorticoid-regulated kinase-1 (SGK1) ( Figure 4 - 11 )

However, the superior bioavailability of properly stored nasal sprays often justifies the additional handling considerations