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To this end, we computed additive genetic associations of the two ratios with 5.55 mio autosomal SNPs at each time point, while adjusting for age, sex, time point-specific HRSD 17 score, the first five PCs to account for population stratification

However, it may not be effective for everyone, especially those with sleep maintenance issues or underlying sleep disorders

The low response rate of lenvatinib, which is mostly caused by resistance development, limits its practical utility in treating patients with advanced liver cancer, even though it is the recommended initial treatment for this condition