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Description

24 S ,25-Epoxycholesterol does not arise from the pathways described above but is synthesised in a shunt of the mevalonate pathway using the same enzymes as for cholesterol, i.e., the squalene mono-oxygenase and lanosterol synthase, by means of which a second epoxyl group is introduced on the other end of squalene from the initial epoxidation, i.e., to give 2,3 S -22 S ,23-dioxidosqualene as an intermediate

doi: 10.1155/2016/5276130 72 HongYAParkCW

Discussion Correlation between GPX1 Pro200Leu SNP and risk of AMI Under normal physiological conditions, GPx-1 reduces oxidative stress tremendously [5]