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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

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doi: 10.1172/JCI21625

Third, the present investigation focused solely on hepatic outcomes, leaving the systemic impact of SR4 on other metabolically active tissues such as skeletal muscles and adipose tissues to be determined