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)., 302, 5646, 841, 2003, Helley MP, Pinnell J, Sportelli C, Tieu K

As oxidative stress increases, further stimulation of pro-inflammatory cytokines such as TNF- and IL-1 increases and contributes to synaptic dysfunction and neuronal degeneration (Dawi et al., 2024)

Amantadine is mainly an antiviral drug where the amantadine helps in reducing the symptoms of PD, particularly dyskinesia (involuntary movements) associated with prolonged use of levodopa