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Rapid endothelial cytoskeletal rearrangement enables early bloodbrain barrier disruption and long-term ischaemic reperfusion brain injury

J Clin Invest (2016) 126:36729

A 38 min linear gradient of 0.1% formic acid in H 2 O (A) and 0.1% formic acid in ACN (B) was used for the fractionation

In 1997, De Flora et al demonstrated that oral administration of NAC (600mg, bid) significantly improved cell-mediated immunity, shifting from anergy to normoergy in seniors (Figure 1A)