neelakantan et al. 2018 biochemical pharmacology 5-amino-1mq NNMT Inhibitor Tablets Emerging opportunities for nicotinamide N-methyltransferase

Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide

Injection Frequency : For patients requiring frequent B12 injections, using a thinner gauge needle (especially for SC injections) can reduce tissue trauma and discomfort over time

Sharing a pic of his B12 bottle

[36] [37] [38] A long-term study where vitamin B 12 was supplemented across a period of 10 years, led to lower levels of weight gain in overweight or obese individuals (p 20% of elderly individuals showed evidence of marginal vitamin B 12 depletion (serum vitamin B 12 : 148221 pmol/L)