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(3) RAPTORmembrane engagement and intermediate enzyme activation

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These results altogether demonstrated the substantially enhanced ferroptosis-based antitumor efficacy of Gi-F-CAA for resolving large tumors in clinic, which might be attributed to the promoted drug delivery efficacy by deep tumor penetration, improved endocytosis, and AEB effect in cells

(There are excess secretions along the in the before picture, causing the vocal cord to appear focally white in the collision zone with the polyp.) Before After A pedunculated left (right side of image) vocal cord hemorrhagic polyp before and after (2 months) microlaryngeal surgical excision.