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Of the 9 referred patients, 3 were treated with oral vitamin B 12 replacement therapy, 2 were given vitamin B 12 injection, and 2 were treated with both oral vitamin B 12 replacement and injection

These areas (upper arms, outer-upper thighs, and belly area) have fewer blood vessels than muscle, which allows nutrients to absorb more slowly and consistently over time

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Owing to their high intracellular abundance, they also serve as indicators of compromised cellular integrity: once released extracellularly, HSP70s act as damage-associated molecular patterns (DAMPs), triggering immune responses through receptors such as the toll-like receptors TLR2 and TLR4 (Theivanthiran et al., 2022