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A scoping review of patient engagement activities during COVID-19: more consultation, less partnership

(4) Most of what a total B12 assay measures is bound to haptocorrin and is not available for uptake by most cells

Fe 2+ + H 2 O 2 Fe 3+ + OH + OH - Hydroxyl radicals generated via this reaction initiate lipid peroxidation, particularly in membranes enriched with polyunsaturated fatty acids (PUFAs), thereby compromising membrane integrity and cellular viability (77, 78)

Lastly, a consensus exists that ferroptosis synergizes with other PCD types in ocular pathologies: autophagy impairment drives ferroptosis of CECs in DED, and necroptosis shares overlapping mechanisms with ferroptosis in RPE cell degeneration (90, 123)