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However, these alterations to the microbial abundance and composition at the phylum, family and genus levels may not sufficient to adequately clarify the changes to the gut microbiota in DN patients, further investigations at the levels of species or strains are necessary in the future

10.1021/acsnano.1c04206 ACS Nano

The size of the LDs is a factor that conditions whether an LD (a) is targeted by microautophagy and digested piece by piece as parts of larger vesicles are pinched off and trapped inside of double-membrane vesicles or (b) is targeted by macroautophagy and digested in lysosomes as a whole small vesicle [82]

In parallel, disruptions in hormonal homeostasis, particularly in steroidogenesis, further compromise follicular development and oocyte quality