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Rigobello MP, Messori L, Marcon G, Agostina Cinellu M, Bragadin M, et al

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Yet, although it is possible to measure a selected protein directly in serum, the level of sensitivity required to quantify many clinically relevant protein biomarkers, such as prostate-specific antigen (PSA) and cardiac troponins, which exist in the low nanogram per milliliter range, require additional sample preparation