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In that study, the authors used young adult (8-10 weeks old) male C57BL/6 mice and performed a dosage screen (from 0.1% to 0.6%) by examining the demyelination in the corpus callosum of cerebral white matter, a brain region where the extent of demyelination can be scored more easily and consistently than the previously described superior cerebellar peduncles with LFB-PAS staining (Skripuletz et al., 2011)

Methylcobalamin is used to treat pernicious anemia and vitamin B12 deficiency, as well as to determine vitamin B12 absorption in the Schilling test

The 30 mL vial format is commonly used in clinical, pharmacy, and healthcare settings where sterile preparation is required under appropriate direction

Kufeld, Roland C