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doi: 10.1146/annurev-nutr-082117-051732 12

These treatments are often sought by individuals looking to address hyperpigmentation, uneven skin tone, or dullness

As a standalone it grades near the bottom of this category, because it raises cortisol, prolactin, and appetite alongside GH (Arvat 1997, Laferrere 2005) while a selective alternative (ipamorelin) delivers the same core GH signal without those effects