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Stearic acid (1 g) and SC (2 mg) were dissolved separately in chloroform (5 mL) and methanol (5 mL), respectively, and afterward mixed

Specifically, the upregulation of the Nrf2 pathway triggers the production of phase II detoxifying/antioxidant enzymes, such as HO-1 and GSTa, while the downregulation of the TLR2/MyD88/NF-B pathway results in a decreased production of pro-inflammatory cytokines, including IL-1, IL-8, and TNF-

Most people notice the changes in stages: Within the first month: Skin typically feels softer and more hydrated, and the complexion looks fresher, though visible whitening at this stage is still subtle

10.5899/2014/ijcmb-00009 40 KimJ.ShimJ.LeeS.ChoW.-H.HongE.LeeJ.et al (2016)