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Studies have shown that arsenic can affect testosterone synthesis in mice by reducing the phosphorylation of protein kinase C, thereby interfering with spermatogenesis 51

Indeed, differences in tryptophan metabolizing bacterial pathways can be found in patients with neurological diseases [209] and psychiatric disorders including BD [210]

The reaction system had a total volume of 20 l, including 10 l of 2 QuantiTect SYBR Green PCR Master Mix (Bio-Rad Laboratories, Inc.), 0.25 l of 10 M forward primer, 0.25 l of reverse primer, 5 l of cDNAs, and 4.75 l of DEPC H2O

Jaksa Vukojevic, Departments of Pharmacology and Pathology, Medical Faculty University of Zagreb, Zagreb 10000, Croatia