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This finding was similar to that of a previous study by The serum iron could reflect hepatic iron accumulation, which is considered an important factor in the progression of liver fibrosis ( On exposure to a toxic dose of APAP, ferrous iron is released into the cytosol from the ruptured lysosomes ( The current results showed that APAP treatment induced a statistically significant increase in MDA and a decrease in GSH levels compared to the control group, while PA produced a significant improvement in oxidative stress by decreasing the MDA level and increasing the GSH level compared to the APAP group

258 Elevated expression of NAMPT maintains the NAD + content to drive the glycolysis, which supports the activation of inflammatory macrophages

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