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Epub 2005 Jul 19

Furthermore, we showed that rv 1127c is more susceptible to bedaquiline (BDQ) than wild-type (WT) Mtb (Mackenzie et al, 2020), and therefore drugs targeting Rv1127c may synergise with BDQ, which is the backbone of the oral, shortened treatments for antibiotic-resistant TB

Despite roughly five decades of work, no DSIP-specific binding site has been cloned, no DSIP gene has been isolated, and no signal-transduction pathway downstream of DSIP binding has been definitively characterized