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Sig Transduct Target Ther

doi: 10.1038/s41590-021-01065-2 123

Key Characteristics: Peptide Classification : Synthetic pentadecapeptide Sequence : GEPPPGKPADDAGLV (a partial sequence of human BPC) Bioactive Functions : Pro-angiogenic, anti-inflammatory, anti-fibrotic Stability : Highly stable in gastric juice (rare for peptides) Origin : Derived from a protein found in the stomachs protective lining Unlike most therapeutic peptides, BPC-157 is active both subcutaneously and orally , and does not require injection to achieve systemic effectsthough injections near the injury site offer superior localized outcomes

Shin J-H et al (2013) Short-term heating reduces the anti-inflammatory effects of fresh Raw Garlic extracts on the LPS-induced production of NO and pro-inflammatory cytokines by downregulating allicin activity in RAW 264.7 macrophages