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Since there are obvious differences between rodent and human physiology, it cannot be ignored that this may have a significant impact on the efficacy and safety of (any) novel agents

After that, the formulations were tested on animals to see whether or not they promoted healthy hair development and hair follicle viability in secondary alopecia

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Immunotherapies like immune checkpoint inhibitors (ICI) and anti-CD38 therapies have shown promising but variable clinical efficacies