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Polyphenols has been shown to affect the gut microbiota and stimulate signaling pathways that promote fatty acid -oxidation, mobilization of adipose tissue through lipolysis, lowering of body weight and fat mass by increasing fat use and energy expenditure through thermogenesis induction, adipose apoptosis, satiety, and an increase in basal metabolic rate (Castro-Barquero et al., 2018)

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This designation permits the use of research materials strictly for in vitro laboratory testing and analytical experimentation