dihexa 10 million times more potent than bdnf Growth factors and their peptide mimetics for treatment of traumatic brain injury Comment "curious" for the full

Comment "curious" for the full newsletter. There's a molecule rumored to be 10 million times more powerful than BDNF for synaptogenesis, neuron growth, learning, and memory. It's called Dihexa. It's gaining Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted AngIV Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP PS1 Mouse via the PI3K AKT Signaling Pathway PMC StayCurious Metabolism Nick Norwitz MD PhD Substack

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