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Results Cytotoxicity of abemaciclib on MCF-7, MDA-MB-231, and MDA-MB-468 breast cancer cell lines (A) and effect of different radiation doses on cell viability of MCF-7 and MDA-MB-231 breast cancer cell lines (B) Figure 1 epitomized that abemaciclib showed anticancer activity on MCF-7, MDA-MB-231, and MDA-MB-486 cell lines with IC 50 equivalents to 57, 32, and 61 M, respectively (Fig